Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.

For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.
Week 2 Case Study (4 cases) with Template: Please follow the the instructions written as per the grading rubric.
COPY AND PASTE THE ENTIRE DOCUMENT BELOW, INCLUDING THE QUESTIONS, AND GIVE ANSWERS WHERE IT SAYS ‘YOUR ANSWER.’

BE VERY BRIEF.
PRIMARY FOCUS: ADVANCED PHARMACOLOGY!

General Directions:
For each of the scenarios below, answer A, B C, D & E using clinical
practice guidelines where applicable.

If any parts of the rubric (A, B C, D & E) do not have an answer, as an example, no prescriptions can be written, please leave the answer blank.
List the drugs (not just the drug class) in discussion (B)

Explain the problem and how you would address the problem (Rationale, C).
If prescribing a new drug, write out a complete medication order (D).
List the 3 references (E)
Written expression and formatting, proper English writing standards, correct grammar and mechanics, and proper punctuation are required.

Question 1. A 52-year-old man was recently discharged from the hospital following treatment for atrial fibrillation. He was discharged on Warfarin 5 mg po q day and Amiodarone 200 mg tid. His INR is 8.8.
What interaction has occurred with these 2 medications?
What changes in his medications would you make?

A. Patient history considered in making the medication selection:
YOUR ANSWER
B. Medication prescribed or changed (Spell out the names of drugs):
YOUR ANSWER
C. Rationale provided to include ‘WHY’ the decision using Clinical Guidelines:
YOUR ANSWER
D. Written medication orders with all 5 aspects required for a valid prescription order (your prescription order):
YOUR ANSWER
E. At least 3 References for the scenario scholarly, peer-reviewed, the past 5 years to include the appropriate clinical practice guidelines if applicable:
YOUR ANSWER

Question 2. A 44-year-old woman is currently taking Glipizide and Phenytoin. She has a new prescription for Ceftriaxone. All three medications are known to be highly protein-bound.

What effect does protein binding have on drug availability?

How would you manage this patient’s medication?

A. Patient history considered in making the medication selection:
YOUR ANSWER
B. Medication prescribed or changed:
YOUR ANSWER
C. Rationale provided to include Current literature to support the rationale with Clinical Guidelines:
YOUR ANSWER
D. Written medication orders with all 5 aspects required for a valid prescription order.
YOUR ANSWER
E. References for the scenario scholarly, peer-reviewed, the past 5 years to include the appropriate clinical practice guidelines if applicable. Use at least 3 sources for each scenario and cite sources using APA format:
YOUR ANSWER

Question 3. Name two drugs that are highly affected by the first pass effect. As a prescriber, what actions would you take in prescribing these drugs to counter the first-pass effect?

A. Patient history considered in making the medication selection:
YOUR ANSWER
B. Medication prescribed or changed:
YOUR ANSWER
C. Rationale provided to include Current literature to support the rationale with Clinical Guidelines:
YOUR ANSWER
D. Written medication orders with all 5 aspects required for a valid prescription order.
YOUR ANSWER
E. References for the scenario scholarly, peer-reviewed, the past 5 years to include the appropriate clinical practice guidelines if applicable. Use at least 3 sources for each scenario and cite sources using APA format:
YOUR ANSWER

Question 4. James is a 49-year-old male who was prescribed atenolol for his high blood pressure. James states that he only occasionally takes the medication because he does not like the side effects.

What information would you provide to the patient at
his visit?

How would you manage his medication?

A. Patient history considered in making the medication selection:
YOUR ANSWER
B. Medication prescribed or changed:
YOUR ANSWER
C. Rationale provided to include Current literature to support the rationale with Clinical Guidelines:
YOUR ANSWER
D. Written medication orders with all 5 aspects required for a valid prescription order.
YOUR ANSWER
E. References for the scenario scholarly, peer-reviewed, the past 5 years to include the appropriate clinical practice guidelines if applicable. Use at least 3 sources for each scenario and cite sources using APA format:
YOUR ANSWER
Learning Resources
Lecturio Resources
Review this week’s videos and content pages in the Lecturio Platform by clicking the button at the end of the page labeled Load Week 2: Learning Resources in a new window.

Lecturio Subscription Process
If you do not already have a subscription to the platform, you will first be taken to a payment screen where you will select the length of access you would like to purchase. Your program will use Lecturio in three courses: NURS 6501 – Advanced Pathophysiology, NURS 6521 – Advanced Pharmacology, and NURS 6512 – Advanced Health Assessment and Diagnostic Reasoning. We recommend purchasing access for the length of time you will need complete these courses. The following resource will guide you through the subscription process: Subscription Process for Lecturio AccessLinks to an external site..

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