Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.
For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.
Week 4 Case Study (4 cases) with Template provided: Please follow the instructions written as per the grading rubric.

COPY AND PASTE THE ENTIRE DOCUMENT BELOW, INCLUDING THE QUESTIONS, AND GIVE ANSWERS WHERE IT SAYS ‘YOUR ANSWER.’
BE VERY BRIEF.
PRIMARY FOCUS: ADVANCED PHARMACOLOGY!
For each of the scenarios below, answer A, B, C, D & E using Clinical
Practice guidelines where applicable.
If any parts of the rubric (A, B, C, D & E) do not have an answer, for example, no prescriptions can be written, please leave the answer blank.
List the drugs (not just the drug class) in discussion (B)
Explain the problem and how you would address the problem (Rationale, C).
If prescribing a new drug, write a complete medication order (D).
List the 3 references (E)
Written expression and formatting, proper English writing standards, correct grammar and mechanics, and proper punctuation are required.
Please provide the answer under Rationale (C) if any additional information is asked.

Question 1. Donald is a 60-year-old male presenting with dyspnea (shortness of breath), chronic productive cough, wheezing, and fatigue. He has smoked one pack of cigarettes per day for the last 40 years. Post-bronchodilator FEV1/FVC ratio < 0.70 confirms persistent airflow limitation. What treatment plan would you implement for this patient? What medication(s) would you prescribe? How would you monitor the effectiveness of this plan? Patient history considered in making the medication selection: YOUR ANSWER B. Medication prescribed or changed (Spell out the names of drugs): YOUR ANSWER C. Rationale provided to include ‘WHY’ the decision using Clinical Guidelines: YOUR ANSWER D. Written medication orders with all 5 aspects required for a valid prescription order (your prescription order: YOUR ANSWER E. At least 3 References for the scenario scholarly, peer-reviewed, the past 5 years to include the appropriate clinical practice guidelines if applicable: YOUR ANSWER Question 2. Allen is a 49-year-old man seeking evaluation for “a burning sensation in my chest,” often after eating and worse at night. He has frequent feelings of bloating and occasional nausea. Allen consumes a diet high in fatty foods and caffeine. He drinks alcohol socially on weekends. PMH includes asthma, diabetes, and hypertension. His current medications include prn albuterol, metformin 1000 mg PO BID, and nifedipine ER 60 mg PO daily. How would you improve his drug therapy plan? What changes would you make? What is your working diagnosis, and what medication would you prescribe? What information would you provide to the patient at his visit? Patient history considered in making the medication selection: YOUR ANSWER B. Medication prescribed or changed: YOUR ANSWER C. Rationale provided to include Current literature to support the rationale with Clinical Guidelines: YOUR ANSWER D. Written medication orders with all 5 aspects required for a valid prescription order. YOUR ANSWER E. References for the scenario scholarly, peer-reviewed, the past 5 years to include the appropriate clinical practice guidelines if applicable. Use at least 3 sources for each scenario and cite sources using APA format: YOUR ANSWER Question 3. Jessica is a 37-year-old female diagnosed with mild persistent asthma. During her visit today, she reports having to use her albuterol four days per week over the past month. Over the past week, she has been using albuterol at least once per day. She reports being awakened by a cough five nights during the last month. Her current medications include fluticasone HFA 44 mcg, two puffs BID, albuterol MDI two puffs Q 4–6 H PRN shortness of breath, Medrol Dosepak, metformin 500 mg PO BID, Inderal LA 160 mg PO daily. How would you step up therapy for this patient? What medication changes would you make? How would you monitor the effectiveness of this plan? What patient teaching would you provide? Patient history considered in making the medication selection: YOUR ANSWER B. Medication prescribed or changed: YOUR ANSWER C. Rationale provided to include Current literature to support the rationale with Clinical Guidelines: YOUR ANSWER D. Written medication orders with all five aspects required for a valid prescription order. YOUR ANSWER E. References for the scenario scholarly, peer-reviewed, the past five years to include the appropriate clinical practice guidelines if applicable. Use at least three sources for each scenario and cite sources using APA format: YOUR ANSWER Question 4 June is a 71-year-old female and has Alzheimer’s Disease x 2 years. She presents with daytime dizziness, fatigue, and increasing forgetfulness. Consider her labs and provide an updated drug therapy plan. Include complete medication orders. How would you monitor drug therapy? Labs: TSH 5 mU/L, vitamin D 29 ng/mL, B12 350 pg/mL, Hb 12.1 g/dL, HgA1C = 5.5% Meds: donepezil 5mg po qhs, zolpidem 10mg po qhs Patient history considered in making the medication selection: YOUR ANSWER B. Medication prescribed or changed: YOUR ANSWER C. Rationale provided to include Current literature to support the rationale with Clinical Guidelines: YOUR ANSWER D. Written medication orders with all 5 aspects required for a valid prescription order. YOUR ANSWER E. References for the scenario scholarly, peer-reviewed, the past 5 years to include the appropriate clinical practice guidelines if applicable. Use at least 3 sources for each scenario and cite sources using APA format: YOUR ANSWER NURS_6521_Week4_Assignment_Rubric NURS_6521_Week4_Assignment_Rubric Criteria Ratings Pts This criterion is linked to a Learning OutcomeScenario 1: Appropriate medication is prescribed or changed. Rationale provided and includes current literature to support decision. All aspects of the patient history are considered in making the medication selection. 15 to >11.0 pts
Excellent
Medication selected is appropriate and considers all of the unique patient characteristics. Rationale for selection is clear, complete, and appropriate.
11 to >7.0 pts
Good
Medication selected might be appropriate but conflicts with the unique patient characteristics. Rationale for selection is clear but lacks discussion about potential prescribing issues.
7 to >3.0 pts
Fair
Medication selected is not appropriate for this patient unique characteristics. Rationale provided is not correct or is flawed in applying the medication to this patient.
3 to >0 pts
Poor
Medication selected is inappropriate or would not be provided based on patient unique characteristics.
15 pts
This criterion is linked to a Learning OutcomeScenario 1: Written medication orders include all 5 aspects required for a valid order. The order is complete, accurate, and appropriate.
3 pts
Complete
Written medication orders includes all 5 aspects required for a valid order. The order is complete, accurate, and appropriate.
0 pts
Poor
The prescription is incomplete. Aspects of a complete order are missing. The order is either incomplete, inaccurate, or inappropriate.
3 pts
This criterion is linked to a Learning OutcomeScenario 1: References for the scenario are within past 5 years and include the appropriate clinical practice guideline if applicable.
4 pts
Excellent
References for the scenario are within past 5 years and include the appropriate clinical practice guideline if applicable. Correct APA format is used.
3 pts
Good
References for the scenario are within past 5 years but do not include the appropriate clinical practice guideline if applicable. Contains a few (1 or 2) APA format errors.
2 pts
Fair
References for the scenario are not from within the past 5 years or do not reflect the content of this scenario and do not include the appropriate clinical practice guideline if applicable. Contains several (3 or 4) APA format errors.
0 pts
Poor
No references are included. References do not reflect the content of this scenario. Appropriate clinical practice guideline is not include. Contains many (≥ 5) APA format errors.
4 pts
This criterion is linked to a Learning OutcomeScenario 1: Written Expression and Formatting – English writing standards: Correct grammar, mechanics, and proper punctuation
3 pts
Excellent
Uses correct grammar, spelling, and punctuation with no errors.
2 pts
Good
Contains a few (1 or 2) grammar, spelling, and punctuation errors.
1 pts
Fair
Contains several (3 or 4) grammar, spelling, and punctuation errors.
0 pts
Poor
Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding.
3 pts
This criterion is linked to a Learning OutcomeScenario 2: Appropriate medication is prescribed or changed. Rationale provided and includes current literature to support decision. All aspects of the patient history are considered in making the medication selection.
15 to >11.0 pts
Excellent
Medication selected is appropriate and considers all of the unique patient characteristics. Rationale for selection is clear, complete, and appropriate.
11 to >7.0 pts
Good
Medication selected might be appropriate but conflicts with the unique patient characteristics. Rationale for selection is clear but lacks discussion about potential prescribing issues.
7 to >3.0 pts
Fair
Medication selected is not appropriate for this patient unique characteristics. Rationale provided is not correct or is flawed in applying the medication to this patient.
3 to >0 pts
Poor
Medication selected is inappropriate or would not be provided based on patient unique characteristics.
15 pts
This criterion is linked to a Learning OutcomeScenario 2: Written medication orders include all 5 aspects required for a valid order. The order is complete, accurate, and appropriate.
3 pts
Complete
Written medication orders includes all 5 aspects required for a valid order. The order is complete, accurate, and appropriate.
0 pts
Poor
The prescription is incomplete. Aspects of a complete order are missing. The order is either incomplete, inaccurate, or inappropriate.
3 pts
This criterion is linked to a Learning OutcomeScenario 2: References for the scenario are within past 5 years and include the appropriate clinical practice guideline if applicable.
4 pts
Excellent
References for the scenario are within past 5 years and include the appropriate clinical practice guideline if applicable. Correct APA format is used.
3 pts
Good
References for the scenario are within past 5 years but do not include the appropriate clinical practice guideline if applicable. Contains a few (1 or 2) APA format errors.
2 pts
Fair
References for the scenario are not from within the past 5 years or do not reflect the content of this scenario and do not include the appropriate clinical practice guideline if applicable. Contains several (3 or 4) APA format errors.
0 pts
Poor
No references are included. References do not reflect the content of this scenario. Appropriate clinical practice guideline is not include. Contains many (≥ 5) APA format errors.
4 pts
This criterion is linked to a Learning OutcomeScenario 2: Written Expression and Formatting – English writing standards: Correct grammar, mechanics, and proper punctuation
3 pts
Excellent
Uses correct grammar, spelling, and punctuation with no errors.
2 pts
Good
Contains a few (1 or 2) grammar, spelling, and punctuation errors.
1 pts
Fair
Contains several (3 or 4) grammar, spelling, and punctuation errors.
0 pts
Poor
Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding.
3 pts
This criterion is linked to a Learning OutcomeScenario 3: Appropriate medication is prescribed or changed. Rationale provided and includes current literature to support decision. All aspects of the patient history are considered in making the medication selection.
15 to >11.0 pts
Excellent
Medication selected is appropriate and considers all of the unique patient characteristics. Rationale for selection is clear, complete, and appropriate.
11 to >7.0 pts
Good
Medication selected might be appropriate but conflicts with the unique patient characteristics. Rationale for selection is clear but lacks discussion about potential prescribing issues.
7 to >3.0 pts
Fair
Medication selected is not appropriate for this patient unique characteristics. Rationale provided is not correct or is flawed in applying the medication to this patient.
3 to >0 pts
Poor
Medication selected is inappropriate or would not be provided based on patient unique characteristics.
15 pts
This criterion is linked to a Learning OutcomeScenario 3: Written medication orders include all 5 aspects required for a valid order. The order is complete, accurate, and appropriate.
3 pts
Complete
Written medication orders includes all 5 aspects required for a valid order. The order is complete, accurate, and appropriate.
0 pts
Poor
The prescription is incomplete. Aspects of a complete order are missing. The order is either incomplete, inaccurate, or inappropriate.
3 pts
This criterion is linked to a Learning OutcomeScenario 3: References for the scenario are within past 5 years and include the appropriate clinical practice guideline if applicable.
4 pts
Excellent
References for the scenario are within past 5 years and include the appropriate clinical practice guideline if applicable. Correct APA format is used.
3 pts
Good
References for the scenario are within past 5 years but do not include the appropriate clinical practice guideline if applicable. Contains a few (1 or 2) APA format errors.
2 pts
Fair
References for the scenario are not from within the past 5 years or do not reflect the content of this scenario and do not include the appropriate clinical practice guideline if applicable. Contains several (3 or 4) APA format errors.
0 pts
Poor
No references are included. References do not reflect the content of this scenario. Appropriate clinical practice guideline is not include. Contains many (≥ 5) APA format errors.
4 pts
This criterion is linked to a Learning OutcomeScenario 3: Written Expression and Formatting – English writing standards: Correct grammar, mechanics, and proper punctuation
3 pts
Excellent
Uses correct grammar, spelling, and punctuation with no errors.
2 pts
Good
Contains a few (1 or 2) grammar, spelling, and punctuation errors.
1 pts
Fair
Contains several (3 or 4) grammar, spelling, and punctuation errors.
0 pts
Poor
Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding.
3 pts
This criterion is linked to a Learning OutcomeScenario 4: Appropriate medication is prescribed or changed. Rationale provided and includes current literature to support decision. All aspects of the patient history are considered in making the medication selection.
15 to >11.0 pts
Excellent
Medication selected is appropriate and considers all of the unique patient characteristics. Rationale for selection is clear, complete, and appropriate.
11 to >7.0 pts
Good
Medication selected might be appropriate but conflicts with the unique patient characteristics. Rationale for selection is clear but lacks discussion about potential prescribing issues.
7 to >3.0 pts
Fair
Medication selected is not appropriate for this patient unique characteristics. Rationale provided is not correct or is flawed in applying the medication to this patient.
3 to >0 pts
Poor
Medication selected is inappropriate or would not be provided based on patient unique characteristics.
15 pts
This criterion is linked to a Learning OutcomeScenario 4: Written medication orders include all 5 aspects required for a valid order. The order is complete, accurate, and appropriate.
3 pts
Complete
Written medication orders includes all 5 aspects required for a valid order. The order is complete, accurate, and appropriate.
0 pts
Poor
The prescription is incomplete. Aspects of a complete order are missing. The order is either incomplete, inaccurate, or inappropriate.
3 pts
This criterion is linked to a Learning OutcomeScenario 4: References for the scenario are within past 5 years and include the appropriate clinical practice guideline if applicable.
4 pts
Excellent
References for the scenario are within past 5 years and include the appropriate clinical practice guideline if applicable. Correct APA format is used.
3 pts
Good
References for the scenario are within past 5 years but do not include the appropriate clinical practice guideline if applicable. Contains a few (1 or 2) APA format errors.
2 pts
Fair
References for the scenario are not from within the past 5 years or do not reflect the content of this scenario and do not include the appropriate clinical practice guideline if applicable. Contains several (3 or 4) APA format errors.
0 pts
Poor
No references are included. References do not reflect the content of this scenario. Appropriate clinical practice guideline is not include. Contains many (≥ 5) APA format errors.
4 pts
This criterion is linked to a Learning OutcomeScenario 4: Written Expression and Formatting – English writing standards: Correct grammar, mechanics, and proper punctuation
3 pts
Excellent
Uses correct grammar, spelling, and punctuation with no errors.
2 pts
Good
Contains a few (1 or 2) grammar, spelling, and punctuation errors.
1 pts
Fair
Contains several (3 or 4) grammar, spelling, and punctuation errors.
0 pts
Poor
Contains many (≥ 5) grammar, spelling, and punctuation errors that interfere with the reader’s understanding.
3 pts
Total Points: 100

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